Some of the differences are subtle, like they end the Laura storyline with Ep #192, we end it with Ep #193. They also consider Adam and Cassandra/VampAng as separate storylines, but they're really very much intertwined. However, perhaps the most glaring difference is that they completely ignore Eps #193 through #204, and to me that is sinful. The introduction of Jason, the start of his blackmailing of Liz, and the James Hall Willie eps are some really great eps. The scenes between Liz and Jason alone are spectacular in those eps - to ignore them is blasphemous! But then they seem to ignore the whole Jason/Liz blackmail plotline entirely because they make no mention of it whatsoever, and to me that is beyond blasphemous because, as I've said numerous times, I think it's the best non-supernatural plotline DS ever did.