Set-up:
Roger: "Oh, how I like a lovely bit of harpoon now and then... I once belonged to the Harvard Harpoon, did you know that? Probably not. As a physician and 'poon enthusiast, you probably do know that ____________! Moby Dick indeed!!"
Lang Lang Lang Went the Trolley: "Did I actually invite you in, or what?"
(Why not let other people write your punchlines for you, when you can't think of one yourself? Hooray for Complete That Phrase!)