Christopher Meloni as a new character who never wears a shirt...
For some reason, I've always thought that Sam Waterston would have made an interesting Barnabas, although I think the role requires a younger actor.
I'd like to see what Faye Dunaway could do with the role of Elizabeth. She certainly has the strength and imperious manner to play the matriarch of a rich and powerful family. For Barnabas, I like the idea of Johnny Depp because of his ability to commit fully to a role, and DS requires total commitment from its actors.