in terms of NODS once it became clear that Frid was not onboard and Selby would be heading up the cast I wonder why they decided to go with a totally new story outside of established series' canon rather that some version of the "werewolf" story with which Quentin had become so strongly associated???
Firstly, DC and Sam Hall didn't believe a werewolf was a strong enough antagonist. (And an interesting bit of film trivia is that, in general, werewolves are the least successful supernatural beings in films. Films featuring werewolves have only done big box office when vampires have also been involved somehow, as in the
Twilight and
Underwolrd series.)
And secondly, DC and Sam Hall wanted to use Angelique as the antagonist, which is why when it was decided that the plot would revolve around Quentin, they went with a reworking of the main 1970PT storyline from the original show.