Let's not have expectations of original cast members. Let's have it be a wonderful unexpected bonus if one turns up in some new DS thing. They've done their bit. Fandom traditionally requires actors to make lots and lots of what are often token appearances, answering a few simple questions for the millionth time, for low pay, mainly for the novelty value of seeing them in the flesh. Wanting to see them in new DS in cameos is the same sort of thing, and I'll say we should value quality over quantity. As you get up in years, you want your time to be spent in a more meaningful way.
If their talents are being used well, that's perfect. Maybe the Dr Mabuse things are an example of good ways to please fans.
Good audios where the actors can sound like the characters they're supposed to be playing still, that would be great too.
Anyway, I don't think the Depp film helped or hurt, except for the fact that no one's going to mount a DS film project right now, just because someone just did that. It sent a ripple out there making it known that DS is "alive" still. It only got made because Depp's a fan, but there could be other pro fans out there.